Maybe it’s a family history that’s been on your mind. Maybe it’s just a general sense that you’d like to understand your health a little better. That curiosity is exactly what Onco-D-Clare and Onco-D-Clare+ were designed around.
These are Oritov’s liquid biopsy laboratory testing panels — a non-invasive, blood-based way to support a conversation with your doctor about your biological health profile, as one part of your broader healthcare picture.
What Does This Test Actually Look At?
It is important to be clear from the outset: Onco-D-Clare is not a diagnostic test and does not detect cancer. It provides supporting biological information for your doctor’s consideration — one piece of information among many your doctor will weigh alongside your full clinical picture, and does not replace your doctor’s clinical assessment.
With that framing in place, here is what the panel actually does. Onco-D-Clare uses PBMC technology — in plain terms, it looks at the genetic activity of certain white blood cells — combined with gene expression analysis across more than 90 genes. This provides supporting biological information for your doctor’s consideration, to be weighed alongside your medical history and other clinical information.
The detailed laboratory methodology, technical protocols, and clinical utility documentation are available to registered healthcare practitioners through Oritov’s Doctor’s Portal.
Onco-D-Clare and Onco-D-Clare+
What Is the Difference?
Onco-D-Clare analyses biological markers in the bloodstream through PBMC gene expression profiling — providing supporting biological information for your doctor’s consideration.
Onco-D-Clare+ is the expanded version. It includes everything in Onco-D-Clare, plus an additional circulating tumour cell (CTC) assessment layer — giving your doctor a broader set of biological information for consideration alongside other clinical information.
- Neither panel diagnoses cancer.
- Neither panel provides a clinical diagnosis or replaces your doctor’s clinical judgement.
- Both are laboratory testing panels that provide supporting biological information for clinician consideration alongside other clinical information.
- Your doctor will advise which version, if either, may be relevant for your situation.
Sample type: Whole peripheral blood
Analysis period: Approximately 7 business days
Final results: 7–10 business days after sample receipt Applicable cancer types:
Your doctor will advise on applicable cancer types for your specific situation.
Where This Fits in Your Healthcare Picture
Cancer development is understood to occur gradually, through a number of biological stages over time. This type of laboratory testing is one tool that may offer additional biological information somewhere along that process. It is intended to sit alongside the diagnostic pathway your doctor already recommends — not instead of it.
Different tests look at different things — imaging, laboratory tests, specialist referrals. Your doctor is best placed to decide which combination makes sense for your individual situation and risk profile.
Is This Something to Discuss With Your Doctor?
Nothing here is a recommendation that you personally undergo testing. This page is provided for general educational purposes only, to help inform the conversation you have with your doctor.
That said, your doctor may raise this as one option worth discussing if your circumstances include:
- A family history of cancer
- Known exposure to environmental or occupational risk factors
- Existing management of chronic inflammation, metabolic syndrome, or immune dysregulation
- An interest in non-invasive, blood-based laboratory testing options as part of your broader health discussions
As with any laboratory testing, whether this is right for you depends entirely on your individual circumstances — something only your doctor can properly assess.
What the Results Mean
Results fall into two categories:
Reactive Result — A reactive immune signal is identified. This does not confirm a cancer diagnosis. It supports a conversation with your doctor about appropriate next steps, which may include further clinical evaluation.
Non-Reactive Result — No reactive immune signal is identified. This supports continuing with the health management plan your doctor advises.
For Onco-D-Clare+, the circulating tumour cell assessment is considered together with the gene expression information — one combined picture for your doctor’s consideration, not two separate findings.
Either way, Onco-D-Clare is not a standalone diagnostic test. It is one part of a broader clinical picture. Further investigation should always be guided by your doctor.
What the Process Looks Like
If you and your doctor decide this is worth exploring, here is what you can generally expect.
It starts with a conversation — you and your doctor discussing whether this test is appropriate for your individual situation. If your doctor recommends proceeding, the next step is a standard blood draw at a participating clinic. Your sample is then sent to the laboratory for analysis, which typically takes about a week. Results are sent to your doctor, usually within 7 to 10 days after the sample arrives at the laboratory.
Then comes the part that matters most — you and your doctor sitting down together to talk through what the results mean, how they fit into your broader healthcare picture, and whether any further evaluation is appropriate.
Frequently Asked Questions
- Is the test painful? No. It requires only a standard blood draw — no biopsy, imaging radiation, or invasive procedure of any kind.
- Does a positive result mean I have cancer? No. A reactive result indicates an immune signal worth discussing further with your doctor. It is not a cancer diagnosis.
- Is this the same as a regular blood test? No. Standard blood panels measure general health markers like cholesterol or blood counts. Onco-D-Clare is a specialised laboratory panel built to evaluate immune cell gene expression patterns — for your doctor’s consideration, not for self-interpretation.
- What is the difference between Onco-D-Clare and Onco-D-Clare+? Onco-D-Clare+ includes everything in Onco-D-Clare, plus an additional circulating tumour cell assessment layer. Neither panel diagnoses cancer. Both provide supporting biological information for your doctor’s consideration alongside other clinical information. Your doctor will advise which, if either, is appropriate for your situation.
- Can this replace imaging or a biopsy? No. Onco-D-Clare does not diagnose cancer and does not replace imaging, biopsy, or histopathology. It provides supporting biological information for your doctor’s consideration — nothing more.
- Can I order this test myself? No. This panel is discussed and ordered through a qualified healthcare professional. Speak with your doctor about whether it may be relevant for your situation.
Speak With Your Doctor First
If something here resonated with you — whether it is family history, lifestyle factors, or general health awareness — the best next step is a conversation with your doctor about whether this is worth exploring.